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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL8197
Molecular formula	C17H20N2O2
IUPAC name	(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 1H-indole-3-carboxylate
Molecular weight	284.359
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.8
Synonyms	HMS2494I19 MolPort-001-903-627 REGID_for_CID_5595 ZNRGQMMCGHDTEI-UHFFFAOYSA-N 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo- AB1004880 BAS 01059550 BRD-A83859836-003-02-8 J-525142 NCGC00015984-05 SMR000060690 (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 1H-indole-3-carboxylate 4CA-1284 ACMC-20bn7f BCPP000032 Enamine_001310 MCULE-8015780530 Oprea1_462281 Tox21 110272 156-45-6 89565-68-4 AKOS022111472 BPBio1_000618 I14-10650 NCGC00015984-02 SCHEMBL463128 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester AC1L1KP5 BBL033991 CCG-205327 L000605 NCGC00162379-01 STL257062 ACMC-20mr3z BDBM50007871 CTK0C2558 HMS1397L12 MLS000055682 Oprea1_655173 VA11915 1H-Indole-3-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester AB00420704_13 AN-15510 BRD-A83859836-001-01-4 ICS 205-930 NCGC00015984-03 SCHEMBL8946882 1H-Indole-3-carboxylic acid, endo-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester AC1Q625H BCP27620 CHEBI:91913 Lopac0_001253 NCGC00162379-02 TA1-RTA 124583-47-7 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate AKOS000573788 Biomol-NT_000158 D0O5CR [ Show all ]
Inchi Key	ZNRGQMMCGHDTEI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3
PubChem CID	5595
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50007871
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
433052	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
433047	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
433051	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
433046	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
433045	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
557268	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
433049	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
433043	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
433044	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
557267	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
557269	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
557270	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
433048	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
433050	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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