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GPCR

Name	Somatostatin receptor type 3
Species	Rattus norvegicus (Rat)
Gene	Sstr3
Synonym	SSR-28 SS3R SS3-R SS-3-R SRIF1C somatostatin receptor 28 SST3 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	428
Amino acid sequence	MAAVTYPSSVPTTLDPGNASSAWPLDTSLGNASAGTSLAGLAVSGILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARMVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRVRSQEPGSGPPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQPGPSGQQQRPCTGTAKEQQLLPQEATAGDKASTLSHL
UniProt	P30936
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3340
IUPHAR	357
DrugBank	N/A

Known ligands

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GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
16295	BDBM84629	C71H81N11O9	1232.5	11 / 12	8.1	No
39298	L-362855	C57H70N10O8	1023.25	9 / 11	5.7	No
40414	BDBM85012	C52H68N12O13S2	1133.31	16 / 13	1.3	No
40416	BDBM85011	C52H68N12O13S2	1133.31	16 / 13	1.3	No
58023	Octreotide	C49H66N10O10S2	1019.25	14 / 13	1.0	No
553530	Octreotide	C49H66N10O10S2	1019.25	14 / 13	1.0	No
96174	BDBM82460	C137H207N41O39S3	3148.59	48 / 44	-16.0	No
553732	Somatostatin 28	C137H207N41O39S3	3148.59	48 / 46	-15.2	No
118927	BIM 23052	C61H75N11O10	1122.34	12 / 13	2.7	No
131133	BDBM82254	C41H60N10O9S2	901.112	13 / 14	0.0	No
148748	BIM-23023	C49H65N11O10S2	1032.25	14 / 13	0.8	No
155253	BIM 23268	C54H67N11O9S2	1078.32	13 / 12	2.8	No
183510	BDBM85230	C54H69N11O9S2	1080.33	13 / 14	2.3	No
213992	BDBM82255	C57H69N11O8S2	1100.37	13 / 12	3.7	No
219839	BDBM85009	C50H66N12O12S2	1091.27	16 / 13	1.1	No
219840	BDBM85013	C50H66N12O12S2	1091.27	16 / 13	1.1	No
223712	SOMATOSTATIN	C76H104N18O19S2	1637.9	24 / 22	-3.1	No
223722	Somatostatin-14	C76H104N18O19S2	1637.9	24 / 22	-3.1	No
554415	seglitide	C44H56N8O7	808.981	8 / 8	3.9	No
229008	BDBM81766	C44H56N8O7	808.981	8 / 8	3.9	No
268945	Lanreotide	C54H69N11O10S2	1096.33	14 / 13	2.5	No
554608	Lanreotide acetate	C54H69N11O10S2	1096.33	14 / 13	2.5	No
275736	BDBM82257	C61H75N11O10	1122.34	12 / 13	4.4	No
499339	CHEMBL3582336	C27H24FN9O2	525.548	8 / 3	2.0	No
325276	Vapreotide	C57H70N12O9S2	1131.38	13 / 13	3.6	No
326207	CH-275	C74H96N14O15S2	1485.79	20 / 18	1.6	No
361202	BIM 23056	C71H81N11O9	1232.5	11 / 12	8.1	No
555105	SS14	C63H88N16O16S2	1389.61	21 / 19	-4.1	No
433000	BDBM85229	C54H69N11O10S2	1096.33	14 / 15	2.0	No