Online Services

●I-TASSER ●D-I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●D-QUARK ●DRfold ●DRfold2 ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●ATGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred ●TCRfinder

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●TM-search ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●DeepMSA2 ●rMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●HPmod ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	P2Y purinoceptor 6
Species	Rattus norvegicus (Rat)
Gene	P2ry6
Synonym	P2Y ATP receptor 6 P2Y purinoceptor 6 P2Y6 P2Y6 receptor pyrimidinergic receptor P2Y uridine nucleotide receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	328
Amino acid sequence	MERDNGTIQAPGLPPTTCVYREDFKRLLLPPVYSVVLVVGLPLNVCVIAQICASRRTLTRSAVYTLNLALADLLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWVVCGVVWLVVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFTALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFVISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPILFYFTQQKFRRQPHDLLQKLTAKWQRQRV
UniProt	Q63371
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3543
IUPHAR	326
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
3878	PSB-6426	C22H29N4O10P	540.466	10 / 5	-1.6	No
4769	CHEMBL517017	C24H32N7O8P	577.535	12 / 5	-1.3	No
26843	PSB 06126	C24H15N2NaO5S	466.443	7 / 2	N/A	N/A
126432	CHEMBL469244	C17H27N4O10P	478.395	10 / 5	-3.0	Yes
157777	Basilen Blue	C29H17ClN7O11S3-3	771.123	18 / 4	4.1	No
162297	CHEMBL608559	C28H17N2O5S-	493.513	7 / 2	6.0	No
167575	CHEMBL496030	C20H13N2O6S-	409.392	8 / 3	3.1	Yes
554132	MRS2567	C16H12N2S2	296.406	4 / 0	6.1	No
184865	CHEMBL468354	C16H25N4O10P	464.368	10 / 5	-2.9	Yes
185445	CHEMBL214698	C9H13BrN2O12P2	483.057	12 / 6	-4.1	No
188335	Acid Blue 25	C20H13N2NaO5S	416.383	7 / 2	N/A	N/A
191425	CHEMBL469067	C17H27N4O10P	478.395	10 / 5	-3.0	Yes
201003	CHEMBL511933	C23H31N4O10P	554.493	10 / 5	-1.7	No
212806	PSB-0952	C21H12FN2NaO7S	478.382	10 / 3	N/A	N/A
226140	CHEMBL464548	C25H34N7O8P	591.562	12 / 5	-1.0	No
236961	CHEMBL590956	C21H12FN2O7S-	455.392	10 / 3	3.1	Yes
242362	CHEMBL463519	C24H33N4O10P	568.52	10 / 5	-1.4	No
244930	CHEMBL513837	C17H26N7O8P	487.41	12 / 5	-2.5	No
246849	CHEMBL256057	C20H13N2O5S-	393.393	7 / 2	3.5	Yes
554680	MRS 2578	C20H20N6S4	472.662	6 / 4	6.3	No
293877	PSB-716	C21H15N2NaO6S	446.409	8 / 2	N/A	N/A
358375	1-Amino-2-(sodiooxysulfonyl)-4-(4-hydroxyphenylamino)-9,10-anthraquinone	C20H13N2NaO6S	432.382	8 / 3	N/A	N/A
368116	CID 136908877	C29H17ClN7Na3O11S3	840.092	15 / 4	N/A	No
370184	CHEMBL257495	C21H15N2O6S-	423.419	8 / 2	3.5	Yes
388141	Uridine 5'-diphosphate	C9H14N2O12P2	404.161	12 / 6	-4.7	No
408787	PSB-0963	C28H17N2NaO5S	516.503	7 / 2	N/A	No
428752	BDBM50268574	C24H15N2O5S-	443.453	7 / 2	4.7	Yes
429157	CHEMBL518544	C23H30N7O8P	563.508	12 / 5	-1.2	No
436692	CHEMBL469243	C18H29N4O10P	492.422	10 / 5	-2.6	Yes

zhanglab

zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417