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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL377828
Molecular formula	C26H29N3O3
IUPAC name	2-[(3R,5R)-5-[4-[5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl]phenyl]pyrrolidin-3-yl]acetic acid
Molecular weight	431.536
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.0
Synonyms	SCHEMBL3496548 2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid BDBM50185526
Inchi Key	AEINVRKYWDZAKS-UZUQRXQVSA-N
Inchi ID	InChI=1S/C26H29N3O3/c30-24(31)15-17-14-23(27-16-17)20-8-10-21(11-9-20)25-28-26(32-29-25)22-12-6-19(7-13-22)18-4-2-1-3-5-18/h6-13,17-18,23,27H,1-5,14-16H2,(H,30,31)/t17-,23-/m1/s1
PubChem CID	44413447
ChEMBL	CHEMBL377828
IUPHAR	N/A
BindingDB	50185526
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3500	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
3497	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
3499	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
3498	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
3501	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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