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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	tranylcypromine
Molecular formula	C9H11N
IUPAC name	(1R,2S)-2-phenylcyclopropan-1-amine
Molecular weight	133.194
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	1.5
Synonyms	GJZ NE64561 (+)-(R)-Tranylcypromine Prestwick2_000173 (1R,2S)-(-)-2-phenylcyclopropylamine trans-(-)-2-Phenylcyclopropanamine (1R-trans)-2-phenyl-cyclopropanamine AK173621 CHEBI:131510 Cyclopropanamine, 2-phenyl-, (1R-trans)- Cyclopropylamine, 2-phenyl-, trans-(.+/-.)- EINECS 205-841-9 l-Tranylcypromine Parnate (Salt/Mix) (-)-Tranylcypromine S-Tranylcypromine (1R,2S)-2-phenylcyclopropanamine trans-2-phenylcyclopropan-1-amine 155-09-9 [(trans)-2-phenylcyclopropyl]amine AC-15970 BRD-K47029922-003-03-4 CHEMBL1179 Cyclopropanamine, 2-phenyl-, trans-(+-)- FCH4526577 LS-58823 Prestwick0_000173 (.+/-.)-Tranylcypromine SPBio_001986 (1R,2S)-trans-tranylcypromine trans-amine 3721-26-4 AELCINSCMGFISI-DTWKUNHWSA-N CBChromo1_000132 CTK3G8797 Cyclopropylamine, 2-phenyl-, trans-(+-)- d-Tranylcypromine HSDB 3404 NSC 80664 (+)-Tranylcypromine rac-trans-Tranylcypromine (1R,2S)-2-phenyl-cyclopropylamine trans-2-phenyl cyclopropylamine (Trans)-2-phenylcyclopropanamine UNII-3E3V44J4Z9 component AELCINSCMGFISI-DTWKUNHWSA-N 8372AH AKOS006282586 CHEBI:94631 Cyclopropanamine, 2-phenyl-, (1R-trans)- (9CI) EN300-197006 Lopac-P-8511 PDSP2_001079 (.+/-.)-trans-2-Phenylcyclopropamine SCHEMBL34339 (1R,2S)-rel-2-phenylcyclopropan-1-amine trans-2-phenylcyclopropanamine 2-Phenyl-1-aminocyclopropane, trans- [trans-2-phenylcyclopropyl]amine AC1L2E8J BRN 2802413 cid_2723716 Cyclopropanamine, 2-phenyl-, trans-(.+/-.)- FCH837207 NCGC00015848-01 Prestwick1_000173 (1R)-1-Amino-2-phenylcyclopropane trans amine (1R,2S)-tranylcypromine Transamine 4694AJ AJ-26319 CCRIS 3344 Cyclopropanamine, 2-phenyl-, (1R,2S)-rel- Cyclopropylamine, 2-phenyl-, trans-(-)- DTXSID2023694 Jatrosom Parnate (+/-)-trans-2-phenylcyclopropylamine rel-Tranylcypromine (1R,2S)-2-phenylcyclopropan-1-amine trans-2-phenyl-cyclopropylamine (tranylcypromine)2-Phenyl-cyclopropylamine ZINC1482197 95-62-5 BDBM50240772 Cyclopropanamine, 2-phenyl-, trans- FCH3609496 LS-58822 PDSP2_001080 (.+/-.)-trans-2-Phenylcyclopropylamine SKF-trans-385 (1r,2s)-rel-2-phenylcyclopropanamine trans-2-Phenylcyclopropylamine 3-12-00-02797 (Beilstein Handbook Reference) AC1Q1HO4 BRN 3195803 CS-0008259 Cyclopropylamine, 2-phenyl-, (1S-trans)- [ Show all ]
Inchi Key	AELCINSCMGFISI-DTWKUNHWSA-N
Inchi ID	InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m0/s1
PubChem CID	19493
ChEMBL	CHEMBL1179
IUPHAR	N/A
BindingDB	50240772
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555494	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
536004	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
3593	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
3591	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
3592	Trace amine-associated receptor 1	Q96RJ0	TAAR1	Homo sapiens (Human)	339

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