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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1086508
Molecular formula	C16H15Cl2F3N4O
IUPAC name	1-(1-cyclopropylethyl)-5-[2,6-dichloro-4-(trifluoromethyl)anilino]-3-methyl-1,2,4-triazin-6-one
Molecular weight	407.218
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	1-(1-cyclopropylethyl)-5-(2,6-dichloro-4-(trifluoromethyl)phenylamino)-3-methyl-1,2,4-triazin-6(1H)-one BDBM50320231
Inchi Key	ALYLZBHAZKKANS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H15Cl2F3N4O/c1-7(9-3-4-9)25-15(26)14(22-8(2)24-25)23-13-11(17)5-10(6-12(13)18)16(19,20)21/h5-7,9H,3-4H2,1-2H3,(H,22,23,24)
PubChem CID	46891033
ChEMBL	CHEMBL1086508
IUPHAR	N/A
BindingDB	50320231
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8669	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415

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