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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCH-900271
Molecular formula	C14H16N2O4
IUPAC name	5-[3-(1-methylcyclopropyl)propyl]-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione
Molecular weight	276.292
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.6
Synonyms	DTXSID00238609 UNII-G2283XQ6VJ BDBM50384612 SB17408 5-(3-(1-Methylcyclopropyl)propyl)-1H-pyrano(2,3-d)pyrimidine-2,4,7(3H)-trione D01DDN SCH900271 G2283XQ6VJ SCH 900271 5-[3-(1-Methylcyclopropyl)propyl]-2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-trione DB12433 SCHEMBL12602910 915210-50-3 GTPL8469 2H-Pyrano(2,3-d)pyrimidine-2,4,7(1H,3h)-trione, 5-(3-(1-methylcyclopropyl)propyl)- CHEMBL2036958 [ Show all ]
Inchi Key	ARJKMWXLIHZLQZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H16N2O4/c1-14(5-6-14)4-2-3-8-7-9(17)20-12-10(8)11(18)15-13(19)16-12/h7H,2-6H2,1H3,(H2,15,16,18,19)
PubChem CID	56950369
ChEMBL	CHEMBL2036958
IUPHAR	8469
BindingDB	50384612
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12520	Hydroxycarboxylic acid receptor 2	Q9EP66	Hcar2	Mus musculus (Mouse)	360
12521	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
12522	Hydroxycarboxylic acid receptor 2	Q80Z39	Hcar2	Rattus norvegicus (Rat)	360
12519	Hydroxycarboxylic acid receptor 3	P49019	HCAR3	Homo sapiens (Human)	387

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