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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL337435
Molecular formula	C35H39Cl2N5O5
IUPAC name	1-[(3S)-4-[(3-cyano-2-methoxynaphthalene-1-carbonyl)-methylamino]-3-(3,4-dichlorophenyl)butyl]-N-methyl-4-(3-oxomorpholin-4-yl)piperidine-4-carboxamide
Molecular weight	680.627
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.6
Synonyms	N/A
Inchi Key	BCFFZBYIVJMBPO-RUZDIDTESA-N
Inchi ID	InChI=1S/C35H39Cl2N5O5/c1-39-34(45)35(42-16-17-47-22-30(42)43)11-14-41(15-12-35)13-10-25(23-8-9-28(36)29(37)19-23)21-40(2)33(44)31-27-7-5-4-6-24(27)18-26(20-38)32(31)46-3/h4-9,18-19,25H,10-17,21-22H2,1-3H3,(H,39,45)/t25-/m1/s1
PubChem CID	10952529
ChEMBL	CHEMBL337435
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20128	Substance-K receptor	P79218	TACR2	Oryctolagus cuniculus (Rabbit)	384
20127	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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