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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Lorpiprazole
Molecular formula	C21H26F3N5
IUPAC name	(1S,8R)-5-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-3,4,6-triazatricyclo[6.3.0.02,6]undeca-2,4-diene
Molecular weight	405.469
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.3
Synonyms	108785-69-9 SCHEMBL15539135 DB09195 UNII-0M14O7T47Q component BNRMWKUVWLKDQJ-YJBOKZPZSA-N
Inchi Key	BNRMWKUVWLKDQJ-YJBOKZPZSA-N
Inchi ID	InChI=1S/C21H26F3N5/c22-21(23,24)16-4-2-5-17(13-16)28-11-9-27(10-12-28)8-7-19-25-26-20-18-6-1-3-15(18)14-29(19)20/h2,4-5,13,15,18H,1,3,6-12,14H2/t15-,18-/m0/s1
PubChem CID	20055414
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB09195
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
548194	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
548197	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
548196	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
548195	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
548198	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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