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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL573284
Molecular formula	C18H21N5O2
IUPAC name	4-[(1R)-1-cyclopropylethyl]-6-[(6-methoxy-2,5-dimethylpyridin-3-yl)amino]-5-oxopyrazine-2-carbonitrile
Molecular weight	339.399
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.9
Synonyms	(R)-4-(1-Cyclopropylethyl)-6-(6-methoxy-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile BDBM50300141
Inchi Key	CLRRTXABLKAYGU-GFCCVEGCSA-N
Inchi ID	InChI=1S/C18H21N5O2/c1-10-7-15(11(2)20-17(10)25-4)22-16-18(24)23(9-14(8-19)21-16)12(3)13-5-6-13/h7,9,12-13H,5-6H2,1-4H3,(H,21,22)/t12-/m1/s1
PubChem CID	44596702
ChEMBL	CHEMBL573284
IUPHAR	N/A
BindingDB	50300141
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
44940	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415

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