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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1269775-42-9
Molecular formula	C24H34ClN7O3
IUPAC name	6-[2-(dimethylamino)ethyl-methylamino]-1,3-dimethyl-N-[(3-propan-2-yloxyphenyl)carbamoyl]pyrazolo[3,4-b]pyridine-5-carboxamide;hydrochloride
Molecular weight	504.032
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	None
Synonyms	KB-65322 CHEMBL1688889 1H-Pyrazolo[3,4-b]pyridine-5-carboxamide,6-[[2-(dimethylamino)ethyl]methylamino]-1,3-dimethyl-N-[[[3-(1-methylethoxy)phenyl]amino]carbonyl]-,Hydrochloride
Inchi Key	CXQUYODBFIUPEH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H33N7O3.ClH/c1-15(2)34-18-10-8-9-17(13-18)25-24(33)27-23(32)20-14-19-16(3)28-31(7)22(19)26-21(20)30(6)12-11-29(4)5;/h8-10,13-15H,11-12H2,1-7H3,(H2,25,27,32,33);1H
PubChem CID	51353695
ChEMBL	CHEMBL1688889
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
53050	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
53048	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374
53051	C-C chemokine receptor type 2	O55193	Ccr2	Rattus norvegicus (Rat)	373
53052	C-C chemokine receptor type 2	P51683	Ccr2	Mus musculus (Mouse)	373
53056	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
53053	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
53049	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
53054	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
53055	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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