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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3416875
Molecular formula	C21H20ClN3O
IUPAC name	(6-chloro-1H-indol-3-yl)-spiro[1,2-dihydroindole-3,4'-piperidine]-1'-ylmethanone
Molecular weight	365.861
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	4.1
Synonyms	1'-[(6-chloro -1H-indol-3-yl)carbonyl]-1,2-dihydrospiro[indole-3,4'-piperidine] BDBM50077248 HKQVHJRZJYPGJU-UHFFFAOYSA-N 1'-[(6-chloro-1H-indol-3-yl)carbonyl]-1,2-dihydrospiro[indole-3,4'-piperidine] SCHEMBL4368502
Inchi Key	HKQVHJRZJYPGJU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H20ClN3O/c22-14-5-6-15-16(12-23-19(15)11-14)20(26)25-9-7-21(8-10-25)13-24-18-4-2-1-3-17(18)21/h1-6,11-12,23-24H,7-10,13H2
PubChem CID	59657691
ChEMBL	CHEMBL3416875
IUPHAR	N/A
BindingDB	50077248
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
446314	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418
446315	Vasopressin V1a receptor	Q62463	Avpr1a	Mus musculus (Mouse)	423

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