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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL221282
Molecular formula	C10H7ClO4S
IUPAC name	5-(5-chlorothiophen-3-yl)-5-methyl-4-oxofuran-2-carboxylic acid
Molecular weight	258.672
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.3
Synonyms	SCHEMBL3100583 (+)-5-(5-chloro-thiophen-3-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid 5-(5-chlorothiophen-3-yl)-5-methyl-4-oxo-4,5-dihydrofuran-2-carboxylic acid (-)-5-(5-chloro-thiophen-3-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid 5-(5-chloro-thiophen-3-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid BDBM50208122 [ Show all ]
Inchi Key	JPZPZVVRVYTIHX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H7ClO4S/c1-10(5-2-8(11)16-4-5)7(12)3-6(15-10)9(13)14/h2-4H,1H3,(H,13,14)
PubChem CID	11379903
ChEMBL	CHEMBL221282
IUPHAR	N/A
BindingDB	50208122
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
157030	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
157029	Hydroxycarboxylic acid receptor 3	P49019	HCAR3	Homo sapiens (Human)	387

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