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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Opc 21268
Molecular formula	C26H31N3O4
IUPAC name	N-[3-[4-[4-(2-oxo-3,4-dihydroquinolin-1-yl)piperidine-1-carbonyl]phenoxy]propyl]acetamide
Molecular weight	449.551
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.6
Synonyms	FT-0700164 N-(3-(4-(4-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)piperidine-1-carbonyl)phenoxy)propyl)acetamide OPC-21268 ACMC-20mu6h CTK0H6673 HY-15009 N-[3-[4-[[4-(3,4-dihydro-2-oxo-1(2H)-quinolinyl)-1-piperidinyl]carbonyl]phenoxy]propyl]acetamide 131631-89-5 BCP14853 DA-46083 LS-9216 AC1L3G6H CHEMBL296908 Fuscoside N-(3-{4-[4-(2-Oxo-3,4-dihydro-2H-quinolin-1-yl)-piperidine-1-carbonyl]-phenoxy}-propyl)-acetamide SCHEMBL3504368 AKOS024457877 D03QHK J-006031 N-[3-[4-[[4-(3,4-Dihydro-2-oxo-1(2H)quinolinyl)-1-piperidinyl]carbonyl]phenoxy]propyl]-acetamide BDBM50029644 EX-A593 MolPort-023-276-994 OPC-1268 Acetamide, N-(3-(4-((4-(3,4-dihydro-2-oxo-1(2H)-quinolinyl)-1-piperidinyl)carbonyl)phenoxy)propyl)- CS-0003694 GTPL2196 N-[3-[4-[4-(2-oxo-3,4-dihydroquinolin-1-yl)piperidine-1-carbonyl]phenoxy]propyl]acetamide ZINC3796262 1-(1-(4-(3-Acetylaminopropoxy)benzoyl)-4-piperidyl)-3,4-dihydro-2(1H)-quinolinone B7537 D08ORO L001417 NCGC00370961-01 [ Show all ]
Inchi Key	KSNUCNRMDYJBKT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H31N3O4/c1-19(30)27-15-4-18-33-23-10-7-21(8-11-23)26(32)28-16-13-22(14-17-28)29-24-6-3-2-5-20(24)9-12-25(29)31/h2-3,5-8,10-11,22H,4,9,12-18H2,1H3,(H,27,30)
PubChem CID	114904
ChEMBL	CHEMBL296908
IUPHAR	2196
BindingDB	50029644
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
177196	Oxytocin receptor	P30559	OXTR	Homo sapiens (Human)	389
177199	Oxytocin receptor	P70536	Oxtr	Rattus norvegicus (Rat)	388
177194	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418
177198	Vasopressin V1a receptor	P30560	Avpr1a	Rattus norvegicus (Rat)	424
177197	Vasopressin V1b receptor	P48974	Avpr1b	Rattus norvegicus (Rat)	425
177195	Vasopressin V2 receptor	Q00788	Avpr2	Rattus norvegicus (Rat)	371
177200	Vasopressin V2 receptor	P30518	AVPR2	Homo sapiens (Human)	371

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