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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL424938
Molecular formula	C11H10O4S
IUPAC name	5-methyl-5-(5-methylthiophen-3-yl)-4-oxofuran-2-carboxylic acid
Molecular weight	238.257
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.8
Synonyms	(-)-5-methyl-5-(5-methyl-thiophen-3-yl)-4-oxo-4,5-dihydro-furan-2-carboxylic acid 5-methyl-5-(5-methylthiophen-3-yl)-4-oxo-4,5-dihydrofuran-2-carboxylic acid GTPL1599 BDBM50208135 compound 5aj [PMID: 17358052] 5-methyl-5-(5-methylthiophen-3-yl)-4-oxofuran-2-carboxylic acid SCHEMBL3100833 (+)-5-methyl-5-(5-methyl-thiophen-3-yl)-4-oxo-4,5-dihydro-furan-2-carboxylic acid D0J7LY 5-methyl-5-(5-methyl-thiophen-3-yl)-4-oxo-4,5-dihydro-furan-2-carboxylic acid [ Show all ]
Inchi Key	NNWGOUJBCKZULC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H10O4S/c1-6-3-7(5-16-6)11(2)9(12)4-8(15-11)10(13)14/h3-5H,1-2H3,(H,13,14)
PubChem CID	11436345
ChEMBL	CHEMBL424938
IUPHAR	1599
BindingDB	50208135
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
228013	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
228014	Hydroxycarboxylic acid receptor 3	P49019	HCAR3	Homo sapiens (Human)	387

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