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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	imetit
Molecular formula	C6H10N4S
IUPAC name	2-(1H-imidazol-5-yl)ethyl carbamimidothioate
Molecular weight	170.234
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	0.2
Synonyms	AC1L1GI2 Carbamimidothioic acid, 2-(1H-imidazol-4-yl)ethyl ester DTXSID8043737 NCGC00015536-02 S-[2-(4-imidazolyl)ethyl]isothiourea 2-(1H-Imidazol-4-yl)ethyl carbamimidothioate AKOS006273468 CHEBI:64156 L000309 NCGC00015536-05 UNII-677MJ4VPZC C17931 CTK4A0786 LS-171808 NCGC00024754-03 {[2-(1H-imidazol-5-yl)ethyl]sulfanyl}methanimidamide 102203-18-9 AC1Q7DRW Carbamimidothioic acid,2-(1H-imidazol-5-yl)ethyl ester GTPL1250 NCGC00015536-03 SCHEMBL114670 2-(1h-imidazol-5-yl)ethyl carbamimidothioate AKOS030611171 Lopac-I-135 NCGC00024754-01 ZINC5425255 677MJ4VPZC C6H10N4S D02RAN NCGC00015536-01 S-(2-(4-Imidazolyl)ethyl)isothiourea ACMC-20m57g CCG-204732 NCGC00015536-04 Tocris-0729 2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide BDBM22911 CHEMBL19439 Lopac0_000645 NCGC00024754-02 {[2-(1H-imidazol-4-yl)ethyl]sulfanyl}methanimidamide [ Show all ]
Inchi Key	PEHSVUKQDJULKE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10)
PubChem CID	3692
ChEMBL	CHEMBL19439
IUPHAR	1250
BindingDB	22911
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
257613	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
257614	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
257616	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445
257617	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
257615	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
554553	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
554554	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391

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