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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Fla-797
Molecular formula	C15H21BrN2O3
IUPAC name	3-bromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide
Molecular weight	357.248
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.3
Synonyms	3-Bromo-N-{[(2S)-1-ethyl-2-pyrrolidinyl]methyl}-2-hydroxy-6-methoxybenzamide BDBM50007534 SCHEMBL9549978 84226-14-2 CHEMBL283099 (-)-(s)-3-bromo-N-[-(1-ethyl-2-pyrrolidinyl)-methyl]-2-hydroxy-6-methoxybenzamide 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide AC1Q2695 KB-287343 3-bromo-n-{[(2s)-1-ethylpyrrolidin-2-yl]methyl}-2-hydroxy-6-methoxybenzamide Benzamide, 3-bromo-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-6-methoxy-, (S)- ZINC28255344 A 35043 Fla 797 3-Bromo-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-6-methoxybenzamide 3-bromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide AKOS030580413 PDSP2_000912 AC1L3SPF 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide [ Show all ]
Inchi Key	PWEZBNRZEHPIIQ-JTQLQIEISA-N
Inchi ID	InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1
PubChem CID	94688
ChEMBL	CHEMBL283099
IUPHAR	N/A
BindingDB	50007534
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
556527	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
270398	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
270403	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
461555	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
270404	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
270399	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
270401	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
270400	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
270402	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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