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Name | Taste receptor type 2 member 14 |
---|---|
Species | Homo sapiens (Human) |
Gene | TAS2R14 |
Synonym | T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1 |
Disease | N/A |
Length | 317 |
Amino acid sequence | MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS |
UniProt | Q9NYV8 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9NYV8 |
3D structure model | This predicted structure model is from GPCR-EXP Q9NYV8. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3309105 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
519706 | SCHEMBL1615993 | C23H29NO4S | 415.548 | 5 / 1 | 4.3 | Yes |
519715 | SCHEMBL1278876 | C23H28N2O5S | 444.546 | 6 / 2 | 2.7 | Yes |
519728 | MLS000092301 | C18H17N3O6S | 403.409 | 7 / 1 | 1.0 | Yes |
519736 | CHEMBL3092263 | C22H27NO5S | 417.52 | 6 / 1 | 4.4 | Yes |
519752 | SCHEMBL1279663 | C16H10N4O2S | 322.342 | 6 / 1 | 3.2 | Yes |
519760 | SCHEMBL1279268 | C22H27NO4S | 401.521 | 5 / 1 | 3.9 | Yes |
519766 | 4-(dibenzylsulfamoyl)benzoic Acid | C21H19NO4S | 381.446 | 5 / 1 | 3.6 | Yes |
519768 | 872621-06-2 | C16H20N4O3S | 348.421 | 6 / 0 | 1.7 | Yes |
519786 | N-cyclohexyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide | C16H21N3O4S | 351.421 | 5 / 1 | 1.6 | Yes |
519814 | SCHEMBL1279135 | C22H26FNO4S | 419.511 | 6 / 1 | 3.6 | Yes |
519845 | (Z)-3-(5-(2,5-dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid | C15H15NO5S2 | 353.407 | 7 / 1 | 2.4 | Yes |
519857 | SCHEMBL1278988 | C19H22FNO4S2 | 411.506 | 7 / 1 | 3.7 | Yes |
519870 | Oprea1_826406 | C23H28BrNO4S | 494.444 | 5 / 0 | 4.9 | Yes |
519890 | SCHEMBL1279307 | C21H18FNO5S | 415.435 | 7 / 2 | 3.3 | Yes |
519896 | SCHEMBL1279537 | C14H19N5O3S | 337.398 | 6 / 0 | 0.6 | Yes |
519929 | MLS001126395 | C17H16FN3O4S | 377.39 | 6 / 1 | 1.8 | Yes |
519961 | SCHEMBL1279003 | C21H24FNO4S | 405.484 | 6 / 1 | 3.7 | Yes |
519966 | SCHEMBL1279380 | C22H20FNO5S | 429.462 | 7 / 1 | 3.7 | Yes |
520035 | SCHEMBL1279440 | C22H23NO4S | 397.489 | 5 / 0 | 4.0 | Yes |
445091 | GSK137647A | C16H19NO3S | 305.392 | 4 / 1 | 3.5 | Yes |
520075 | AC1NDBVX | C24H29ClN2O2S | 445.018 | 3 / 2 | 5.6 | No |
520080 | N-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide | C9H9N3O4S | 255.248 | 5 / 3 | -0.6 | Yes |
520088 | Oprea1_594647 | C23H28ClNO4S | 449.99 | 5 / 0 | 4.9 | Yes |
520113 | SCHEMBL1279688 | C21H20N2O5S | 412.46 | 7 / 1 | 2.8 | Yes |
520116 | Oprea1_513452 | C20H19NO6S | 401.433 | 7 / 1 | 2.7 | Yes |
520119 | SCHEMBL1615032 | C21H18FNO4S | 399.436 | 6 / 1 | 3.7 | Yes |
520131 | SCHEMBL1279598 | C23H20N2O5S | 436.482 | 7 / 1 | 3.3 | Yes |
538574 | SCHEMBL1279804 | C23H23NO5S | 425.499 | 6 / 1 | 4.0 | Yes |
520148 | 4-[((4-methoxybenzyl){[(2-methoxyphenyl)amino]carbonothioyl}amino)methyl]cyclohexanecarboxylic acid | C24H30N2O4S | 442.574 | 5 / 2 | 4.1 | Yes |
520163 | SCHEMBL1278748 | C22H21NO6S | 427.471 | 7 / 2 | 3.2 | Yes |
520172 | SCHEMBL1279013 | C22H19NO6S | 425.455 | 7 / 1 | 3.4 | Yes |
520260 | Oprea1_386690 | C25H32N2O5S | 472.6 | 6 / 1 | 3.4 | Yes |
520272 | SCHEMBL1279325 | C22H20FNO4S | 413.463 | 6 / 1 | 4.0 | Yes |
520273 | AC1NSIFU | C18H25N5O3S | 391.49 | 6 / 0 | 1.9 | Yes |
520325 | SCHEMBL1279102 | C22H19NO5S | 409.456 | 6 / 1 | 3.3 | Yes |
520326 | SCHEMBL1279249 | C22H21NO4S2 | 427.533 | 6 / 1 | 4.1 | Yes |
520330 | SCHEMBL1279479 | C21H18FNO4S | 399.436 | 6 / 1 | 3.7 | Yes |
540088 | SCHEMBL1279010 | C25H25NO5S | 451.537 | 6 / 1 | 4.3 | Yes |
520365 | SCHEMBL1279106 | C23H23NO6S | 441.498 | 7 / 1 | 3.5 | Yes |
520377 | N-(3-fluoro-2-methylphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide | C17H16FN3O4S | 377.39 | 6 / 1 | 1.8 | Yes |
520402 | SCHEMBL1279120 | C21H19NO5S | 397.445 | 6 / 2 | 3.2 | Yes |
520406 | SCHEMBL1279662 | C22H20ClNO5S | 445.914 | 6 / 1 | 4.2 | Yes |
520408 | SCHEMBL1279439 | C22H21NO4S | 395.473 | 5 / 1 | 3.9 | Yes |
520422 | SCHEMBL1279628 | C19H12N4O3S | 376.39 | 7 / 1 | 3.9 | Yes |
520432 | SCHEMBL1279660 | C21H18ClNO4S | 415.888 | 5 / 1 | 4.2 | Yes |
520462 | SCHEMBL1279764 | C22H21NO6S | 427.471 | 7 / 2 | 3.2 | Yes |
520477 | SCHEMBL1279497 | C23H23NO4S | 409.5 | 5 / 1 | 4.4 | Yes |
520491 | SCHEMBL1279183 | C22H21NO4S | 395.473 | 5 / 1 | 3.9 | Yes |
520492 | AC1NLP7L | C18H17N3O6S | 403.409 | 7 / 1 | 1.0 | Yes |
520493 | SCHEMBL1279528 | C22H23NO6S | 429.487 | 7 / 1 | 3.6 | Yes |
520494 | SMR000081775 | C17H15N3O6S | 389.382 | 7 / 1 | 1.1 | Yes |
520511 | SCHEMBL1279684 | C25H32N2O2S | 424.603 | 3 / 2 | 5.4 | No |
520522 | UNM000000883401 | C24H30ClNO4S | 464.017 | 5 / 0 | 5.2 | No |
520523 | Oprea1_014947 | C19H17NO5S | 371.407 | 6 / 1 | 2.7 | Yes |
520535 | AC1OMQJ3 | C18H18N4O3S | 370.427 | 5 / 1 | 1.4 | Yes |
520537 | SCHEMBL1279321 | C22H19F2NO5S | 447.453 | 8 / 1 | 3.8 | Yes |
520538 | CHEMBL3092287 | C22H21NO5S | 411.472 | 6 / 1 | 3.6 | Yes |
520544 | Oprea1_007249 | C21H21NO6S | 415.46 | 7 / 1 | 3.0 | Yes |
520567 | SCHEMBL1279638 | C22H20ClNO5S | 445.914 | 6 / 1 | 4.2 | Yes |
520583 | SCHEMBL1279068 | C23H22FNO6S | 459.488 | 8 / 1 | 3.6 | Yes |
520603 | AC1NT3IW | C25H30BrNO6S | 552.48 | 7 / 0 | 4.7 | No |
520623 | SCHEMBL1615515 | C21H18FNO4S | 399.436 | 6 / 1 | 3.7 | Yes |
520634 | SCHEMBL1615156 | C16H13ClFN3O4S | 397.805 | 6 / 1 | 2.1 | Yes |
520650 | SCHEMBL1279146 | C16H17NO6S2 | 383.433 | 8 / 1 | 2.4 | Yes |
520657 | SCHEMBL1278774 | C22H18N2O4S | 406.456 | 6 / 1 | 3.3 | Yes |
520662 | SCHEMBL1279288 | C17H19NO5S | 349.401 | 6 / 1 | 2.4 | Yes |
520672 | SCHEMBL1279232 | C23H22FNO6S | 459.488 | 8 / 1 | 3.6 | Yes |
520679 | SCHEMBL1616132 | C21H25FN2O4S | 420.499 | 7 / 2 | 3.0 | Yes |
520690 | SCHEMBL1279599 | C20H23FN2O4S | 406.472 | 7 / 1 | 2.6 | Yes |
520710 | SCHEMBL1278727 | C23H23NO6S | 441.498 | 7 / 1 | 3.5 | Yes |
520749 | Oprea1_395930 | C22H26FNO5S | 435.51 | 7 / 1 | 3.6 | Yes |
520764 | SCHEMBL1279410 | C22H18N2O4S | 406.456 | 6 / 1 | 3.3 | Yes |
543408 | SCHEMBL1279284 | C23H21NO5S | 423.483 | 6 / 1 | 3.6 | Yes |
520795 | SCHEMBL1615022 | C22H21NO5S | 411.472 | 6 / 1 | 3.6 | Yes |
520798 | SCHEMBL1278766 | C23H23NO5S | 425.499 | 6 / 1 | 3.9 | Yes |
520811 | N-(2,3-dimethylquinoxalin-6-yl)-1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide | C20H19N5O4S | 425.463 | 7 / 1 | 1.4 | Yes |
520815 | 1,4-dimethyl-2,3-dioxo-N-[4-(pyridin-2-ylmethyl)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide | C22H20N4O4S | 436.486 | 6 / 1 | 2.2 | Yes |
520816 | SCHEMBL1278600 | C22H21NO5S | 411.472 | 6 / 1 | 3.6 | Yes |
520829 | SCHEMBL1279324 | C21H18ClNO4S | 415.888 | 5 / 1 | 4.2 | Yes |
520881 | SCHEMBL1279128 | C21H18FNO4S | 399.436 | 6 / 1 | 3.7 | Yes |
520894 | SCHEMBL1615513 | C22H21NO5S | 411.472 | 6 / 1 | 3.6 | Yes |
520906 | SCHEMBL1278916 | C22H21NO6S | 427.471 | 7 / 2 | 3.2 | Yes |
520909 | 4-Diisobutylsulfamoyl-benzoic acid | C15H23NO4S | 313.412 | 5 / 1 | 4.1 | Yes |
544582 | SCHEMBL1279151 | C23H21NO5S | 423.483 | 6 / 1 | 3.8 | Yes |
520958 | SCHEMBL1279014 | C23H23NO6S | 441.498 | 7 / 1 | 3.5 | Yes |
520960 | SCHEMBL1615476 | C23H27FN2O5S | 462.536 | 7 / 2 | 2.8 | Yes |
520966 | SCHEMBL1279785 | C23H23NO5S | 425.499 | 6 / 1 | 3.9 | Yes |
520982 | SCHEMBL1279561 | C24H25NO7S | 471.524 | 8 / 1 | 3.5 | Yes |
520994 | Oprea1_056229 | C22H26FNO4S | 419.511 | 6 / 1 | 4.0 | Yes |
520996 | AC1LT76E | C19H18N4O4S | 398.437 | 6 / 1 | 2.3 | Yes |
521007 | SCHEMBL1615817 | C21H18FNO4S | 399.436 | 6 / 1 | 3.7 | Yes |
521032 | SCHEMBL1615504 | C23H29NO5S | 431.547 | 6 / 1 | 3.9 | Yes |
521035 | SCHEMBL1278819 | C20H19NO6S | 401.433 | 7 / 1 | 2.7 | Yes |
521038 | 1,3-dimethyl-N-(2-methylphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide | C17H17N3O4S | 359.4 | 5 / 1 | 1.7 | Yes |
521041 | SCHEMBL1615502 | C23H26N2O4S | 426.531 | 6 / 1 | 3.6 | Yes |
521048 | SCHEMBL1279372 | C23H23NO6S | 441.498 | 7 / 1 | 3.5 | Yes |
521056 | 4-{[{[(3-chloro-4-methylphenyl)amino]carbonothioyl}(4-methoxybenzyl)amino]methyl}cyclohexanecarboxylic acid | C24H29ClN2O3S | 461.017 | 4 / 2 | 5.2 | No |
521061 | 899748-38-0 | C17H22N4O3S | 362.448 | 5 / 0 | 1.3 | Yes |
521087 | 1,3,7-trimethyl-5-((2-oxo-2-(piperidin-1-yl)ethyl)thio)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione | C16H21N5O3S | 363.436 | 6 / 0 | 1.0 | Yes |
521096 | AC1NESFS | C15H19N5O4S | 365.408 | 7 / 0 | -0.2 | Yes |
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