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| Name | Prokineticin receptor 1 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | PROKR1 |
| Synonym | VEGFR-1 PKR1 PK-R1 GPR73a GPR73 [ Show all ] |
| Disease | N/A |
| Length | 393 |
| Amino acid sequence | METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLDLKTIGMPATEEVDCIRLK |
| UniProt | Q8TCW9 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | Q8TCW9 |
| 3D structure model | This predicted structure model is from GPCR-EXP Q8TCW9. |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL5649 |
| IUPHAR | 335 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 536103 |  CHEMBL3938854 | C18H22ClN3O2S | 379.903 | 4 / 1 | 3.7 | Yes |
| 533933 |  CHEMBL3983601 | C17H23ClN4O2S | 382.907 | 5 / 1 | 3.0 | Yes |
| 536118 |  CHEMBL3941024 | C19H22ClN3O4S | 423.912 | 6 / 1 | 2.7 | Yes |
| 7879 |  CHEMBL557700 | C23H27Cl2N7O3 | 520.415 | 4 / 3 | 2.8 | No |
| 464004 |  CHEMBL3622088 | C20H23N5O | 349.438 | 4 / 2 | 2.4 | Yes |
| 553298 |  N-{2-Furan-2-yl-1-[(pyridin-3-ylmethyl)-carbamoyl]-vinyl}-benzamide | C20H17N3O3 | 347.374 | 4 / 2 | 2.2 | Yes |
| 533956 |  CHEMBL3901692 | C16H19Cl2N3O3S | 404.306 | 5 / 1 | 3.6 | Yes |
| 533957 |  CHEMBL3924529 | C17H21ClFN3O2S | 385.882 | 5 / 1 | 3.6 | Yes |
| 533962 |  CHEMBL3975166 | C21H25N3O3S | 399.509 | 5 / 0 | 3.7 | Yes |
| 533976 |  CHEMBL3944037 | C20H23N3O3S | 385.482 | 5 / 1 | 3.6 | Yes |
| 536435 |  CHEMBL3900231 | C19H23ClFN3O2S | 411.92 | 5 / 1 | 3.8 | Yes |
| 533977 |  CHEMBL3973527 | C18H23ClFN3O2S | 399.909 | 5 / 0 | 3.6 | Yes |
| 536450 |  CHEMBL3987113 | C19H26ClN3O3S | 411.945 | 5 / 1 | 3.1 | Yes |
| 21095 |  CHEMBL560451 | C19H27Cl2N7O2 | 456.372 | 3 / 3 | 2.8 | Yes |
| 465658 |  CHEMBL3622087 | C22H28N4O | 364.493 | 2 / 0 | 3.0 | Yes |
| 534006 |  CHEMBL3894644 | C18H24Cl2N4O2S | 431.376 | 5 / 0 | 3.8 | Yes |
| 25685 |  CHEMBL565054 | C22H27N7O4 | 453.503 | 5 / 3 | 0.7 | Yes |
| 534018 |  CHEMBL3966784 | C17H21Cl2N3O2S | 402.334 | 4 / 0 | 4.1 | Yes |
| 536742 |  CHEMBL3941566 | C18H21ClFN3O2S | 397.893 | 5 / 0 | 3.2 | Yes |
| 534024 |  CHEMBL3920852 | C18H24FN3O4S | 397.465 | 7 / 0 | 2.5 | Yes |
| 534045 |  CHEMBL3958623 | C18H23ClFN3O3S | 415.908 | 6 / 1 | 3.4 | Yes |
| 534047 |  CHEMBL3985917 | C16H19Cl2N3O3S | 404.306 | 5 / 0 | 3.6 | Yes |
| 534054 |  CHEMBL3898520 | C19H25ClFN3O3S | 429.935 | 6 / 0 | 3.5 | Yes |
| 468083 |  CHEMBL3622086 | C23H29N5O | 391.519 | 4 / 0 | 3.3 | Yes |
| 534105 |  CHEMBL3981546 | C17H21Cl2N3O3S | 418.333 | 5 / 2 | 3.1 | Yes |
| 534106 |  CHEMBL3946318 | C17H21Cl2N3O3S | 418.333 | 5 / 0 | 3.7 | Yes |
| 534126 |  CHEMBL3981069 | C18H20Cl2N4O2S | 427.344 | 5 / 1 | 3.4 | Yes |
| 534132 |  CHEMBL3897887 | C18H24ClN3O4S | 413.917 | 6 / 0 | 3.0 | Yes |
| 50140 |  CHEMBL563069 | C20H22ClN7O2 | 427.893 | 3 / 3 | 1.3 | Yes |
| 470426 |  CHEMBL3622089 | C20H24ClN5O | 385.896 | 3 / 1 | 3.2 | Yes |
| 534184 |  CHEMBL3943549 | C18H21ClN4O2S | 392.902 | 5 / 1 | 2.8 | Yes |
| 534203 |  CHEMBL3932513 | C16H19Cl2N3O3S | 404.306 | 5 / 1 | 3.6 | Yes |
| 534210 |  CHEMBL3977298 | C16H21ClN4O2S | 368.88 | 5 / 2 | 3.0 | Yes |
| 534243 |  CHEMBL3986936 | C17H22Cl2N4O2S | 417.349 | 5 / 1 | 3.7 | Yes |
| 534253 |  CHEMBL3900223 | C18H25N3O3S | 363.476 | 5 / 1 | 3.1 | Yes |
| 534255 |  CHEMBL3973051 | C21H28BrN3O4S | 498.436 | 6 / 0 | 3.4 | Yes |
| 79050 |  triazine compound PC1 | C23H29N7O3 | 451.531 | 4 / 3 | 1.5 | Yes |
| 537934 |  CHEMBL3927248 | C18H25N3O3S | 363.476 | 5 / 1 | 2.3 | Yes |
| 534261 |  CHEMBL3983167 | C18H22F3N3O3S | 417.447 | 8 / 0 | 3.3 | Yes |
| 537970 |  CHEMBL3889670 | C18H19ClN4O2S | 390.886 | 5 / 1 | 2.6 | Yes |
| 534264 |  CHEMBL3984251 | C18H21ClF3N3O3S | 451.889 | 8 / 0 | 3.9 | Yes |
| 538135 |  CHEMBL3905529 | C18H24ClN3O3S | 397.918 | 5 / 2 | 2.6 | Yes |
| 95313 |  CHEMBL550034 | C22H33N7O4 | 459.551 | 5 / 3 | 0.6 | Yes |
| 538429 |  CHEMBL3982097 | C17H21ClFN3O2S | 385.882 | 5 / 1 | 3.4 | Yes |
| 534390 |  CHEMBL3980507 | C17H21ClFN3O2S | 385.882 | 5 / 1 | 3.6 | Yes |
| 538637 |  CHEMBL3981959 | C17H18Cl2FN3O2S | 418.308 | 5 / 1 | 3.6 | Yes |
| 534397 |  CHEMBL3910847 | C17H19ClF3N3O3S | 437.862 | 8 / 1 | 3.9 | Yes |
| 538783 |  CHEMBL3974875 | C17H22ClN3O3S | 383.891 | 5 / 2 | 2.4 | Yes |
| 534417 |  CHEMBL3908365 | C18H21Cl2N3O3S | 430.344 | 5 / 0 | 3.3 | Yes |
| 538799 |  CHEMBL3893095 | C19H26ClN3O3S | 411.945 | 5 / 0 | 2.9 | Yes |
| 534418 |  CHEMBL3956849 | C19H26ClN3O3S | 411.945 | 5 / 0 | 3.5 | Yes |
| 538833 |  CHEMBL3917980 | C20H23ClN4O2S | 418.94 | 5 / 1 | 3.4 | Yes |
| 534435 |  CHEMBL3959736 | C16H21ClN4O4S | 400.878 | 7 / 1 | 2.2 | Yes |
| 534436 |  CHEMBL3943716 | C16H19Cl2N3O3S | 404.306 | 5 / 0 | 3.3 | Yes |
| 539010 |  CHEMBL3919323 | C17H19ClFN3O2S | 383.866 | 5 / 1 | 2.9 | Yes |
| 534445 |  CHEMBL3981081 | C18H22F3N3O4S | 433.446 | 9 / 0 | 3.6 | Yes |
| 124187 |  CHEMBL551383 | C21H24ClN7O3 | 457.919 | 4 / 3 | 1.3 | Yes |
| 534451 |  CHEMBL3912835 | C17H22ClN3O3S | 383.891 | 5 / 0 | 3.3 | Yes |
| 534455 |  CHEMBL3926322 | C17H22FN3O4S | 383.438 | 7 / 1 | 2.5 | Yes |
| 534458 |  CHEMBL3905662 | C17H23ClN4O4S | 414.905 | 7 / 0 | 2.3 | Yes |
| 534462 |  CHEMBL3942364 | C17H21F2N3O4S | 401.429 | 8 / 1 | 2.6 | Yes |
| 534473 |  CHEMBL3974638 | C16H20ClN3O3S | 369.864 | 5 / 0 | 2.9 | Yes |
| 534485 |  CHEMBL3975181 | C18H22N4O3S | 374.459 | 6 / 0 | 2.1 | Yes |
| 534499 |  CHEMBL3956657 | C18H23Cl2N3O3S | 432.36 | 5 / 1 | 3.1 | Yes |
| 534511 |  CHEMBL3967729 | C21H28ClN3O4S | 453.982 | 6 / 0 | 3.3 | Yes |
| 137513 |  triazine compound PC7 | C21H24FN7O3 | 441.467 | 5 / 3 | 0.8 | Yes |
| 534519 |  CHEMBL3917467 | C18H23F2N3O4S | 415.456 | 8 / 0 | 2.6 | Yes |
| 139520 |  CHEMBL459142 | C25H31N7O3 | 477.569 | 4 / 3 | 1.9 | Yes |
| 534527 |  CHEMBL3938627 | C16H19ClFN3O3S | 387.854 | 6 / 1 | 3.1 | Yes |
| 144532 |  CHEMBL560171 | C23H29N7O4 | 467.53 | 5 / 3 | 1.1 | Yes |
| 534571 |  CHEMBL3889563 | C18H24ClN3O4S | 413.917 | 6 / 2 | 2.4 | Yes |
| 540084 |  CHEMBL3898347 | C20H21FN4O2S | 400.472 | 6 / 1 | 2.6 | Yes |
| 534642 |  CHEMBL3945817 | C19H27N3O3S | 377.503 | 5 / 0 | 3.1 | Yes |
| 534649 |  CHEMBL3959797 | C17H22FN3O3S | 367.439 | 6 / 0 | 2.5 | Yes |
| 534656 |  CHEMBL3955663 | C19H26ClN3O2S | 395.946 | 4 / 1 | 4.4 | Yes |
| 534658 |  CHEMBL3963619 | C18H25ClN4O2S | 396.934 | 5 / 0 | 3.2 | Yes |
| 534680 |  CHEMBL3895489 | C17H22ClN3O2S | 367.892 | 4 / 1 | 3.5 | Yes |
| 484038 |  CHEMBL3622090 | C18H20ClFN4O | 362.833 | 5 / 1 | 2.8 | Yes |
| 554139 |  IS20 | C23H21N3O3 | 387.439 | 4 / 2 | 3.1 | Yes |
| 534684 |  CHEMBL3895674 | C20H28ClN3O4S | 441.971 | 6 / 0 | 3.0 | Yes |
| 173906 |  CHEMBL564734 | C21H25N7O4 | 439.476 | 5 / 4 | 0.3 | Yes |
| 540482 |  CHEMBL3935247 | C18H24ClN3O3S | 397.918 | 5 / 0 | 3.5 | Yes |
| 534690 |  CHEMBL3974465 | C17H19ClF3N3O3S | 437.862 | 8 / 0 | 3.6 | Yes |
| 540518 |  CHEMBL3953005 | C19H19F3N4O3S | 440.441 | 9 / 1 | 3.1 | Yes |
| 540529 |  CHEMBL3949632 | C18H22ClF2N3O2S | 417.9 | 6 / 1 | 4.1 | Yes |
| 534762 |  CHEMBL3964334 | C18H23Cl2N3O2S | 416.361 | 4 / 0 | 4.1 | Yes |
| 534771 |  CHEMBL3448261 | C16H20FN3O3S | 353.412 | 6 / 1 | 2.5 | Yes |
| 534787 |  CHEMBL3976696 | C17H19ClN4O3S | 394.874 | 6 / 1 | 2.7 | Yes |
| 541178 |  CHEMBL3973243 | C17H18Cl2FN3O2S | 418.308 | 5 / 1 | 3.6 | Yes |
| 203257 |  CHEMBL563890 | C17H18ClN7O3 | 403.827 | 4 / 3 | 0.5 | Yes |
| 206726 |  CHEMBL561309 | C18H27N7O3 | 389.46 | 4 / 3 | 0.4 | Yes |
| 534833 |  CHEMBL3919321 | C17H21BrFN3O3S | 446.335 | 6 / 0 | 3.2 | Yes |
| 541655 |  CHEMBL3899695 | C18H24ClN3O3S | 397.918 | 5 / 0 | 3.5 | Yes |
| 541719 |  CHEMBL3906648 | C19H26ClN3O3S | 411.945 | 5 / 1 | 3.3 | Yes |
| 534878 |  CHEMBL3912045 | C17H20ClF2N3O3S | 419.872 | 7 / 0 | 3.2 | Yes |
| 221052 |  CHEMBL552457 | C22H27N7O4 | 453.503 | 5 / 3 | 0.7 | Yes |
| 534917 |  CHEMBL3964020 | C17H18Cl2F3N3O3S | 472.304 | 8 / 0 | 4.2 | Yes |
| 542083 |  CHEMBL3893804 | C17H19ClFN3O2S | 383.866 | 5 / 1 | 3.1 | Yes |
| 542465 |  CHEMBL3937917 | C18H24ClN3O2S | 381.919 | 4 / 1 | 3.8 | Yes |
| 245410 |  CHEMBL556890 | C18H21N7O4 | 399.411 | 5 / 3 | 0.1 | Yes |
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